How should APV be applied?

The correct application method for APV, or Acyclovir, is vaginally, particularly when it’s intended for the treatment of viral infections such as genital herpes. This route allows for localized treatment in the affected area, which can help to minimize systemic side effects and provide more direct therapeutic action where it is needed most.

Choosing this method also aligns with the intended therapeutic use of medication in addressing infections directly at the site of disease, rather than introducing it into the bloodstream or other systemic routes that could lead to increased side effects or diminished local efficacy. For instance, oral application would disperse the drug systemically and may not achieve the intended local levels necessary for effective treatment. Topical application is another route that can be valid in other contexts but does not apply to Acyclovir in this situation. Inhaling would not be applicable as it does not target the area of infection, and the dosage forms typically available for Acyclovir do not support this method of administration.