What do SSRIs stand for in pharmacology?

SSRIs stand for Selective Serotonin Reuptake Inhibitors, which is a class of medications primarily used to treat depression and anxiety disorders. These drugs work by selectively inhibiting the reuptake of serotonin in the brain, which increases the availability of serotonin in the synaptic cleft and enhances neurotransmission. This mechanism is thought to contribute to mood regulation and the alleviation of symptoms associated with depression.

The specificity of SSRIs in targeting serotonin reuptake makes them different from other classes of antidepressants, which may affect multiple neurotransmitters. The term "selective" indicates their focus on serotonin, differentiating them from other drugs that may influence norepinephrine or dopamine levels, hence their use in conditions where enhancing serotonin levels is particularly beneficial.