Which document indicates the changes in medication dosage instructed by a physician?

The correct answer is the prescription order, as it serves as the formal document through which a physician communicates specific instructions about a patient's medication regimen, including any changes in dosage. This order provides critical information, such as the name of the medication, the dosage amount, frequency of administration, and duration of therapy, allowing pharmacists and pharmacy technicians to ensure the patient receives the appropriate therapy as prescribed by the healthcare provider.

It is important to note that while the medication profile, patient history report, and medication administration record contain valuable information about the patient's medication history and current treatments, they do not specifically detail the changes in dosage as directly as a prescription order does. The medication profile summarizes a patient's medications, but it lacks the specificity of dosage changes. The patient history report focuses more on the broader medical history rather than current medication dosages, and the medication administration record is utilized for documenting the administration of medications rather than communicating changes in dosage from a healthcare provider.